Powerful, Safe, and efficient cyanoborohydride chemistry for reductive amination
Biotage® MP-Cyanoborohydride is a macroporous polymer supported cyanoborohydride. It is a versatile reducing agent for the reductive amination of carbonyl compounds and reduction of imines. The reaction work-up protocol is greatly simplified by using the solid supported reagent. Specifically, compared with the small molecule sodium cyanoborohydride, it is reported that toxic cyanide is not released on reaction workup and therefore does not contaminate the product or pose a danger towards the user.