Fermenter BioFlo® 510 series

The BioFlo 510 is a compact sterilizable-in-place fermentation system ideal for pilot to small scale production processes. The modular design features a wide variety of standard options allowing this system to be flexible enough to meet most process requirements. Gas flow › Various combinations of one, two, three or four TMFCs: 0.06  –   3 SLPM 0.3  –   15 SLPM 0.6  –   32 SLPM 1  –   64 SLPM › Overlay (valve only) Exhaust line › Exhaust condenser › Manual or automatic pressure control Impellers › Rushton-type – Used commonly for robust cell lines such as bacteria, yeasts, and algae, where maximum OTR is desired. Provided as standard on BioFlo 510 fermentors › Pitched-blade – Commonly used with mammalian, insect or other shear sensitive cell lines for batch, fed-batch or continuous cultures. Produces axial and radial mixing. › Marine – Commonly used with mammalian, insect, or other shear sensitive cell lines for batch, fed-batch or continuous cultures. Produces axial mixing Sensors › Single or redundant pH/DO › Redox › Foam/level Addition and sampling › Resterilizable sampling valve › Resterilizable addition valves (4 max) › Resterilizable addition/harvest valve with dip tube (2 max) › 1.5 in sanitary fitting 7-port septum › Addition vessels (glass/stainless steel) › Sterile sampling assembly Validation › Basic Package › Basic Plus Package › Enhanced Package Utility regulator & pre-filter kits › Process air pre-filter/regulator kit › Instrument air pre-filter/regulator kit › Water pre-filter/regulator kit › Process steam regulator kit › Utility steam pre-filter/regulator kit › Utility connection kit