Pharma extruder GJE series

The Genizer Jacketed Liposome Extruders is compressed air-driven and temperature-controlled, from testing to manufacturing production of liposome and lipopolyplex, for drug and gene delivery. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The process is relatively gentle, exposing the formulation to moderate pressures up to 500 psi at controlled temperatures. The Genizer Jacketed Extruder offers virtually no dead-volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals. Application: Liposome extrusion Performance: No dead volume The Jacketed Extruder can control the temperature of the extrusion Specifications Catalog No. - GJE-10mL - GJE-100mL - GJE-800mL - GJE-3000mL Sample Size - 10mL - 100mL - 800mL - 3,000mL Cooling - Jacketed - Jacketed - Jacketed - Jacketed Dimensions - 23cm×13cm×25cm - 23cm×20cm×32cm - 25cm×25cm×37cm - 30cm×25cm×55cm Weight - 4kg - 7kg - 20kg - 45kg Min. Sample Size - 5mL - 10mL - 120mL - 800mL Application - Liposome formulation up to production scale Max. Pressure - 80 psi-500 psi Max. Temp. - 80ºC (176ºF) Power Type - Compressed gas Nano-membrane - Track-etched membrane Cleaning - Flush to clean/CIP/SIP Sterilization - Whole unit autoclavable