Fast, gentle optically sectioned 3D images of large or living specimens with the ability to access structures that were previously inaccessible via standard confocal or widefield techniques.
Long Term Imaging for Large Samples with Light Sheet Microscopy
Imagine you had access to an imaging system that could deliver optical sections of large samples, with virtually no phototoxicity or bleaching and with high temporal resolution.
That is exactly what Lightsheet Z.1 from ZEISS does. The unique Multiview light sheet fluorescence microscope allows you to record the development of large, living samples and gently image them to deliver exceptionally high information content.
It is also fast: Lightsheet Z.1 is the tool you need to get optical sections at unprecedented speed. Acquire images of your whole sample volume at sub-cellular resolution – in a fraction of the time it takes using other techniques.
Fast, Light-Efficient Data Acquisition
Light sheet fluorescence microscopy or LSFM splits fluorescence excitation and detection into two separate light paths, with the axis of illumination perpendicular to the detection axis. That means you illuminate a single thin section of your sample at one time, generating an inherent optical section by exciting only fluorescence from the in-focus plane. No pinhole or image processing is required for light sheet microscopy.