The IA-5133B-U2i is an Intelligent-Appliance enclosed Relay Multiplexer with 64/32/16-ch, organized as Single Pole, Dual Pole, two Dual Pole and Quad Pole formats. This Relay Multiplexer solution includes a "break before make" built-in mechanism and can be used as an electronic sequencer, a random state activator or multi-state activator, software defined. The IA-5133B-U2i includes both USB and RS-232 ports that can be directly connected to any PC computer, or can be chained by its built in Daisy Chain facility. The IA-5133B-U2i is a Series-3000 compatible, with the same software support package, Visual Studio drivers, open source examples and immediate operation utilities.