The DSR-M dissolution sampling robot is designed specifically for the sample transfer and sample processing from a six to twelve vessel dissolution bath. This unique versatile instrument allows samples to be collected over very short time intervals. The DSR-M can be equipped to collect, dilute or process samples for following UV-Visible or HPLC measurements. It can also be used for dissolution medium replenishment to conform to USP/EP volume loss rules.
Automated Sampling
To offer the highest volume precision, between six and thirteen piston pumps are used for sample removal and media refilling (optional), one dedicated pump for each channel. No time consuming pump calibration is needed. The advanced design of the system means that it is always ready for operation. The pumps are integrated into the DSR-M as a compact CAT-M pump module. The sample preparation station, Z-arm and needle, can be used to dispense into septa sealed HPLC vials or dilute the samples for later UV/VIS analysis. Keeping the samples in sealed vials helps to avoid evaporation, especially if sustained release samples are tested.
The DSR-M can be connected to a Pharma Test PTWS-series and PT-DT70 dissolution bath. If the DSR-M is connected to a PTWS 820D, PTWS 620, PTWS 1220, PTWS D620 or PTWS 1420 dissolution bath the sampling probes are connected to its EPE auto sampling manifold. The motorized EPE lowers the sampling probes into the corresponding sampling position which can be set for either 500 or 900ml total media volume. Sampling cycle information is programmed directly at the dissolution bath using the method filing system.