Differential scanning calorimeter RS-DSC

DSCshort-term thermal stabilitythermal stability screening

For scientists in the demanding world of biologic drug development, understanding biomolecule stability under thermal variations is crucial to ensure product quality, and support regulatory approval. Short term thermal stability testing reveals a compound’s resilience to thermal stress, predicts shelf life, and ensures efficacy. The requirement for accurately measuring this in a high throughput environment is challenging without disrupting processes or meeting tight timelines. To meet this demand, we designed the TA Instruments RS-DSC (Rapid Screening-Differential Scanning Calorimeter), a new solution for the rapid characterization of biotherapeutic thermal stability. The TA Instruments RS-DSC Can Help Accelerate thermal stability testing: The TA Instruments RS-DSC provides detailed insights into drug product thermal stability significantly quicker by analyzing up to 24 samples simultaneously. The TA Instruments RS-DSC’s technology also simplifies characterization of highly concentrated drug products. Improve efficiency: The TA Instruments RS-DSC ensures materials are used efficiently by utilizing disposable MFCs (Micro Fluidic Chips) to contain the sample. MFCs require <15 ul sample volume, and the design facilitates a cleaner, more streamlined operation by reducing the need for tedious sample dilution, repetitive instrument cleaning, and contamination risks. Make more informed decisions: NanoAnalyze™ Software effortlessly handles the increased data volume produced by the TA Instruments RS-DSC, providing in-depth, precise insights about a molecule’s thermal stability and thermodynamic properties.