Increase your confidence in peak purity using the Thermo Scientific Vanquish Loop Heart-Cut 2D-LC System. This two-dimensional LC system (LC-LC) enables you to collect one or multiple fractions of the first-dimension separation in a sample loop and transfer the cut-out fraction(s) in an automated workflow to a second-dimension separation. Heart-Cut 2D-LC can reveal hidden impurities that co-elute with the analytes of interest by using two complementary column chemistries to gain more separation power. The system is configured using modules from the Vanquish Core HPLC, Vanquish Flex UHPLC or Horizon UHPLC systems, retaining all the performance, robustness and ease of use of the Vanquish LC platform.
Greater confidence
Collect one or multiple fractions of the first-dimension separation in a sample loop and transfer the cut-out fraction(s) to a second-dimension column with complementary column chemistry in an automated workflow for more confidence in peak purity.
Flexibility
The modularity of Vanquish LC systems makes it easy to build a system to best suit your application requirements and upgrade a standard HPLC instrument to more advanced 2D-LC configurations when you need to address more challenging analyses.
Save time and resources
The integrated LC-LC system in combination with automated workflows, with predefined fractionation and transfer steps, allow for unattended sample analysis while reducing human error and saving time and bench space compared to offline approaches.