Silica HPLC column XTerra®

First Generation Hybrid Columns Based upon first generation hybrid (inorganic/organic) particles, the XTerra® family of HPLC columns enables chromatographers to perform high pH drug discovery, method development and purification separations. XTerra® Columns combine the best properties of silica and polymeric bonded phases with patented Hybrid Particle Technology that replaces one out of every three silanols with a methyl group during particle synthesis. This hydrophobicity is distributed through the entire structure of the particle backbone, resulting in a rugged hybrid particle that can be operated at high speeds, high temperatures and at high pH. The presence of 33% fewer residual silanols (after endcapping and bonding) also means that XTerra columns give exceptionally sharp, high-efficiency peaks for basic compounds. Method Development XTerra Columns wide pH range enables method development scientists to operate at the mobile phase pH necessary for optimal selectivity. These HPLC columns make it possible to develop robust separations in less time.